Yes, both is possible. You can select single or all frames from the index tab. Clicking on the scan button starts the batch scanning of the selected frames. You can set differnet scan settings for each frame in the prescan and image correction tabs. If you set the index scan setting to quality in the preferences a prescan is performed while index-scanning, so you can switch between the prescans without delay. After you have choosen the scan settings and made the image correction go to the index scan tab and select the pictures to be scan in a row.